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(a) The average AUC and AUPRC values over the terms in GO Slim for DIFFUSE (blue), DIFFUSE without CRF (green), DIFFUSE without using conserved domains (pink) and DIFFUSE without using sequences (yellow). (b) Average importance scores for conserved domain regions and non-conserved domain regions are calculated for each isoform-GO term pair. There is a clearly a significant difference between these two regions as supported by the one-sided Wilcoxon test (****P < 0.0001)
