Table 1.
In vitro activity of different antimicrobial agents against 56 penicillin non-susceptible pneumococcal isolates.
Antimicrobial | MIC (µg/mL) | Range | MIC interpretation according to EUCAST | |||
---|---|---|---|---|---|---|
MIC50 | MIC90 | % Susceptible | % Intermediate | % Resistant | ||
Ceftaroline | 0.032 | 0.094 | 0.008–0.19 | 100 | 0 | 0 |
Ceftobiprole | 0.032 | 0.25 | 0.012−0.5 | 100 | 0 | 0 |
Dalbavancin | 0.012 | 0.016 | 0.006–0.023 | NA | NA | NA |
Delafloxacin | ≤0.002 | 0.003 | ≤0.002–0.006 | NA | NA | NA |
Eravacycline | 0.008 | 0.012 | 0.006–0.047 | NA | NA | NA |
Tedizolid | 0.19 | 0.25 | 0.094–0.38 | NA | NA | NA |
Telavancin | ≤0.002 | 0.002 | ≤0.002–0.003 | NA | NA | NA |
Abbreviations: MIC, minimal inhibitory concentration; EUCAST, The European Committee on Antimicrobial Susceptibility Testing.