Table 3.
Parameters | No. | Event | Median OS | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|---|---|
(95% CI) | HR (95% CI) | p-value | HR(95%CI) | p-value | |||
DFI | |||||||
<2 years | 15 | 9 | 18.4 (8.8–27.9) | 0.7 (0.3–1.8) | 0.51 | ||
≥2 years | 15 | 11 | 15.2 (11.5–18.9) | ||||
No. of metastatic sites | |||||||
1 | 9 | 5 | 31 (4.8–57.7) | 2.4 (0.7–7.3) | 0.13 | ||
≥2 | 22 | 15 | 15.2 (12.6–17.9) | ||||
Liver metastasis | |||||||
Yes | 5 | 3 | 10.0 (5.6–14.1) | 4.0 (1.1–15.3) | 0.038 | 2.9(0.7–11.2) | 0.12 |
No | 25 | 17 | 18.4 (7.0–29.7) | ||||
LI | |||||||
<0.56 | 16 | 8 | 26.4 (8.6–44.4) | 1.9 (0.7–4.8) | 0.18 | ||
≥0.56 | 15 | 12 | 14.0 (10.7–17.1) | ||||
SUV max | |||||||
<4.31 | 15 | 9 | 22.9 (7.6–38.3) | 1.4 (0.5–3.5) | 0.473 | ||
≥4.31 | 16 | 11 | 15.2 (11.5–18.9) | ||||
MTV (mL) | |||||||
<1.25 | 15 | 8 | 26.5 (10.1–42.8) | 1.6 (0.6–4.3) | 0.28 | ||
≥1.25 | 16 | 12 | 13.9 (10.5–17.3) | ||||
TLG (g) | |||||||
<3.54 | 16 | 8 | 31.2 (18.5–44.1) | 3.1 (1.2–8.6) | 0.029 | 2.8 (1.0–7.9) | 0.04 |
≥3.54 | 15 | 12 | 13.9 (10.9–16.8) |
Abbreviations: OS, overall survival; DFI, disease-free interval; LI, low index; SUV, standard uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis.