Table 3.
Mean non-adherence scores
| Conditionc | Mean (standard deviation) MAR-Scale scorea, b for the 19 items | |||||
|---|---|---|---|---|---|---|
| Daily oral | Daily injections | Daily topicals | Weekly orals | Weekly injections | Weekly topical | |
| Diabetes | 1.78 (7.30) | 2.00 (9.08) | 6.12 (14.41) | |||
| Arthritis | 3.92 (11.15) | 17.52 (31.26) | 4.93 (13.00) | 4.61 (10.08) | 7.08 (12.20) | 6.94 (9.72) |
| Lupus | 7.18 (18.81) | 6.25 (12.61) | ||||
| Migraine | 5.41 (12.44) | 4.28 (8.65) | ||||
| Osteoporosis | 4.70 (12.93) | 1.84 (6.03) | ||||
| Pain | 3.81 (10.11) | 6.42 (14.03) | 4.55 (8.58) | 11.08 (15.54) | 6.06 (10.00) | |
| IBD | 5.82 (12.48) | 17.23 (17.87) | ||||
| GERD/Heartburn | 2.79 (8.96) | 5.07 (10.66) | ||||
| Chronic constipation | 5.48 (14.09) | 3.31 (6.52) | ||||
| IBS | 4.31 (10.33) | 4.57 (8.69) | ||||
| Psoriasis | 14.07 (21.76) | 10.55 (16.74) (22) | 3.63 (10.23) | 4.38 (9.97) | 11.24 (18.01) | 4.36 (7.98) |
| Eczema | 11.05 (18.60) | 4.01 (8.64) | 12.69 (16.11) | 23.69 (16.55) | 3.84 (9.38) | |
| Multiple sclerosis | 3.54 (8.05) | 3.00 (5.80) (14) | 5.67 (12.92) | |||
| Epilepsy | 3.89 (11.47) | |||||
| Sleep condition | 4.34 (10.88) | 5.44 (9.39) | 15.43 (13.29) | |||
| Depression | 3.53 (10.14) | 8.54 (12.37) | ||||
| Overactive bladder | 4.43 (11.51) | 7.09 (10.93) | ||||
Notes: aThe MAR-Scale score can range from 0 to 133 for medicines taken daily and 0–76 for medicines taken weekly. Higher scores indicate more complex non-adherence with more reasons and days. bFor medicines, the mean MAR-Scale scores were calculated only if the sample size was more than 30 or at least 10% of the patients taking oral medicines for that condition. For example, in multiple sclerosis, there were only 89 patients on oral medicines. Thus, if there were at least nine patients on the other modes of administration, it was included. cEczema = Eczema/Atopic Dermatitis/Dermatitis; Sleep condition = Sleep difficulties/Insomnia/Narcolepsy/Sleep Apnea; Pain = Pain/Fibromyalgia/Diabetic Neuropathic Pain; Overactive bladder = Wet/Dry/Stress Urinary Incontinence; Osteoporosis = Osteoporosis/Osteopenia; Arthritis = Rheumatoid Arthritis/Psoriatic Arthritis/Osteoarthritis/Ankylosing Spondylitis; Diabetes = Type 1/Type 2/Latent Autoimmune Diabetes in Adults.
Abbreviations: GERD, GastroEsophageal Reflux Disease; IBD, Inflammatory Bowel Disease; IBS, irritable bowel syndrome.