Table 1.
Demographic data of studied groups and clinicopathologic characteristics of psoriatic patients
| Cases | Control | t-test | P-value | |
|---|---|---|---|---|
| Age, years | ||||
| Mean ± SD | 39.3±14.9 | 33.6±4.7 | U=1.8 | 0.07 |
| Median | 37.5 | 34 | ||
| Range | 17–75 | 23–42 | ||
| Sex n, (%) | ||||
| Male | 18 (69.2) | 20 (76.9) | χ2=0.39 | 0.53 |
| Female | 8 (30.8) | 6 (23.1) | ||
| Family history n, (%) | ||||
| Positive | 2 (7.7) | — | — | — |
| Negative | 24 (92.3) | — | — | — |
| Duration, years | ||||
| Mean ± SD | 10.3±3.2 | — | — | — |
| Median | 10 | — | — | — |
| Range | 2–15 | — | — | — |
| Age at onset, years | ||||
| Mean ± SD | 29.1±13.8 | — | — | — |
| Median | 27 | — | — | — |
| Range | 13–61 | — | — | — |
| PASI score | ||||
| Mean ± SD | 23.5±13.7 | — | — | — |
| Median | 21.5 | — | — | — |
| Range | 4–53 | — | — | — |
| Severity n, (%) | ||||
| Mild | 1 (3.8) | — | — | — |
| Moderate | 6 (23.1) | — | — | — |
| Severe | 19 (73.1) | — | — | — |
| Stability: | ||||
| Stable | 21 (80.8) | — | — | — |
| Progressive | 5 (19.2) | — | — | — |
| Histopathological parameters | ||||
| Epidermal changes | ||||
| Acanthosis n, (%) | ||||
| Present | 26 (100) | — | — | — |
| Absent | 0 | — | — | — |
| Parakeratosis n, (%) | ||||
| Confluent | 5 (19.2) | — | — | — |
| Focal | 21 (80.8) | — | — | — |
| Granular cell layer n, (%) | ||||
| Absent | 18 (69.2) | — | — | — |
| Partially absent | 8 (30.8) | — | — | — |
| Munro microabcesses n, (%) | ||||
| Present | 21 (80.8) | — | — | — |
| Absent | 5 (9.2) | — | — | — |
| Suprapaillry epidermis n, (%) | ||||
| Normal | 5 (7.7) | — | — | — |
| Thin | 21 (92.3) | — | — | — |
| Spongyform pustules of Kogoj n, (%) | ||||
| Present | 21 (80.8) | — | — | — |
| Absent | 5 (9.2) | — | — | — |
| Tip of rete ridge n, (%) | ||||
| Normal | 6 (23.1) | — | — | — |
| Coalescent | 20 (76.9) | — | — | — |
| Dermal changes | ||||
| Dilated blood vessels n, (%) | ||||
| Present | 22 (84.6) | — | — | — |
| Absent | 4 (15.4) | — | — | — |
| Perivascular lymphocytic infiltrate n, (%) | ||||
| Present | 21 (80.8) | — | — | — |
| Absent | 5 (9.2) | — | — | — |
Abbreviation: PASI, Psoriasis Area and Severity Index.