Polar bear exhibits divergent CN profiles compared with brown bear and black bear. PCA of gene CN across all bear individuals for genes showing agreement between the two CN estimation methods. (A) All CN-variable genes (VST > 0; 4,698 genes), (B) differentiated genes (VST > 0.22; 197 genes), and (C) highly differentiated genes (VST > 0.35; 134 genes). The percentage of variance explained by PC1, PC2, and PC3 are provided below each plot.