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. 2019 Jun 17;116(27):13641–13650. doi: 10.1073/pnas.1904249116

Fig. 1.

Fig. 1.

Ventral striatal dopamine levels relate to lever pressing during exposure to inescapable aversive stimuli. (A) Trial structure for the inescapable footshock task. (B) Representative color plots of voltammetry recordings in the VMS illustrating the dopamine response to the aversive cue (Left), the aversive stimulus (Center), and the safety period (Right). (C) Average dopamine response across electrodes. (D) Lever presses across training sessions, ***P < 0.001 main effect of pressing. (E) Occurrence of lever presses within trials, **P < 0.01 post hoc Sidak’s test. (F) Cue-elicited freezing, ***P < 0.01 main effect of pressing. (G) Average dopamine traces over all training sessions. (H–J) Timecourse of the dopamine response during the cue (H), the footshock bout (I), and the safety period (J), **P < 0.01, ***P < 0.001 main effect of pressing.