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. 2019 Jul 3;14:4833–4847. doi: 10.2147/IJN.S208292

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© 2019 Chiu et al.

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SPR sensorgrams of response curves for the assay of human hCG protein in the clinical serum samples. (A) SPR sensorgram of the peptide probe and BSA on the carboxyl-GO-based SPR aptasensor immobilization process steps of continuous reaction. (B) Sensorgram of two analysis cycles of a peptide–hCG protein interaction at different clinical serum sample concentrations. (C) The relationship between hCG protein and SPR angle shift was evaluated in serum samples with different dilutions. (D) Calibration plot for SPR angle shift with different dilutions of hCG serum samples at optimized conditions.

Abbreviations: SPR, surface plasmon resonance; hCG, human chorionic gonadotropin; GO, graphene oxide.