Table 2:

Regression analyses on the relationship of APOE ε4 on abnormal sleep patterns. NAD: no/low AD load; IAD: intermediate AD load; HAD: high AD load; OR: odds ratio.

		Males		Females
Variable		Unadjusted	Adjusted	Unadjusted	Adjusted
		OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
NAD
	APOE ε4	1.13 (0.62–2.07)	1.05 (0.57–1.94)	2.48 (1.26–4.86) *	2.16 (1.06–4.40) *
	Age last visit		0.98 (0.96–1.00)		0.95 (0.93–0.98) *
	Depression		1.00 (0.52–1.93)		1.49 (0.63–3.53)
	Anxiety		2.88 (1.02–8.14) *		1.28 (0.66–2.48)
IAD
	APOE ε4	1.20 (0.56–2.57)	1.26 (0.58–2.72)	1.39 (0.57–3.41)	1.34 (0.53–3.36)
	Anxiety		2.02 (0.89–4.55)		2.90 (1.08–7.80) *
HAD
	APOE ε4	1.16 (0.71–1.91)	1.13 (0.68–1.70)	1.88 (1.03–3.41) *	1.55 (0.83–2.90)
	Age last visit		1.00 (0.98–1.01)		0.99 (0.97–1.01)
	Yrs Education		1.03 (0.98–1.09)		1.05 (0.97–1.13)
	Depression		1.62 (1.10–2.41) *		1.41 (0.85–2.32)
	Anxiety		1.87 (1.28–2.73) *		2.25 (1.38–3.65) *

^*p ≤ 0.05.