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. 2019 Jul 8;17:124. doi: 10.1186/s12916-019-1359-9

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Trends in mortality and clinical features of severe malaria over time. The trends over time are shown for clinical features of severe malaria among all children admitted with a parasite threshold of > 2500 μl. The percentage of children with a parasite threshold > 2500/μl where the relevant observation was positive is shown in red bars (left y-axis), and the absolute number of cases where the observation was positive is shown by the blue line (right y-axis). a All severe. b Cerebral. c Anaemia. d Resp. distress. e Other. f Mortality