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. 2019 Jul 3;2(7):e196700. doi: 10.1001/jamanetworkopen.2019.6700

Figure 4. Sex Bias vs Number of Study Participants for 14 371 Cardiovascular Clinical Studies, Estimated From Published Articles by the PubMed-Extract Algorithm.

Figure 4.

Each point represents 1 article. A, With studies as the measurement unit of sex bias, each study point has equal intensity of blue shade and contribution to the overall estimate of sex bias. B, With participants as the measurement unit of sex bias, study point orange shade intensity is proportional to the number of participants; small studies are essentially invisible and contribute little to the overall sex bias estimate.