Figure 9.

LINC01116 silencing or miR-136 over-expression inhibits the tumor growth and LNM in vivo. (A) The tumor growth rate in each group of TSCCa cell line. (B) The tumor growth rate in each group of Tca83 cell line. (C) HE staining in each group of tumors. (D) The number of LNM of TSCCa cell line. (E) The number of LNM of Tca83 cell line. The data were measurement data and expressed as mean±standard deviation. This experiment was repeated 3 times to obtain the mean value. The comparisons among multiple groups were performed based on one-way ANOVA and the value comparisons at different time points were performed using repeated measures ANOVA. *p<0.05 vs the blank and NC groups.

Abbreviations: LNM, lymph node metastasis; miR-136, microRNA-136; HE, hematoxylin-eosin; ANOVA, analysis of variance; NC, negative control.