Hemin induced oxidative stress and SESN2 can be reduced by NAC in CRC cells.
(A) Representative green fluorescence images, (B) quantification of DCFDA staining, (C) Western blot analysis and (D) quantification in HCT116 and RKO CRC cells. Cells were treated with 100 μM hemin or 1 mM NAC as indicated for overnight. *p < .05, **p < .01 and ***p < .001.