Table 1.
Characteristics for Patients with SLE and Controls
| Patients with SLE (N=899) |
Matched Controls (N=4,172) |
p-value | |
|---|---|---|---|
| Demographics | |||
| Age (years) | 42 [30-53] | 41 [30-52] | 0.77 |
| Female (%) | 807 (90) | 3811 (91) | 0.13 |
| Race | 0.30 | ||
| White (%) | 635 (71) | 3018 (72) | |
| Black (%) | 214 (24) | 969 (23) | |
| Other or Unknown (%) | 50 (6) | 185 (4) | |
| Ethnicity | 0.12 | ||
| Hispanic (%) | 25 (3) | 132 (3) | |
| BMI (kg/m2) | 26.7 [23.1-32.2] | 27.8 [23.5-33.3] | <0.001 |
| Person years of observation time | 6.5 [3.4-10.6] | 7.6 [3.7-12.2] | <0.001 |
| Blood Pressure Observations | |||
| Number of readings per person | 21 [9-44] | 17 [8-35] | <0.001 |
| Number of dates with | 19 [9-38] | 15 [7-29] | <0.001 |
| observations per person | |||
| Renal Function | |||
| Creatinine (mg/d) | 0.82 [0.70-1.00] | 0.80 [0.70-0.90] | <0.001 |
| eGFR (ml/min/1.73m2) | 85 [65-106] | 90 [75-109] | <0.001 |
| Cardiovascular Measures | |||
| Total Cholesterol (mg/dL) | 180 [152-208] | 189 [161-218] | <0.001 |
| HDL-C (mg/dL) | 52 [39-64] | 54 [44-67] | <0.001 |
| LDL-C (mg/dL) | 99 [79-124] | 107 [85-131] | <0.001 |
| Triglycerides (mg/dL) | 123 [86-180] | 101 [70-155] | <0.001 |
| Hypertension (%) | 479 (53) | 1837 (44) | <0.001 |
| Antihypertensive agents | |||
| ACE inhibitors | 354 (39) | 1209 (29) | <0.001 |
| ARBs | 253 (28) | 743 (18) | <0.001 |
| Beta-blockers | 439 (49) | 1608 (39) | <0.001 |
| Calcium channel blockers | 359 (40) | 1094 (26) | <0.001 |
| Others | 518 (58) | 1888 (45) | <0.001 |
^
Continuous values are presented as median [interquartile range] and categorical variables are presented as N (%).
*
N=5071 except as noted for the following variables: BMI (N=4709), Creatinine (N=4737), EGFR (N=4764), Cholesterol (N=2648), HDL-C (N=2569), LDL-C (N=2487), and Triglycerides (N=2623).