Table 1.
Day of quinidine | Dose of quinidine (mg/kg/day) | QTc (ms) | Efficacy and outcome with quinidine |
---|---|---|---|
Case 1 | |||
1 | 5 | 437 | |
4 | 10 | 433 | |
13 | 15 | 358 | |
20 | 20 | 351 | 30% seizure reduction |
57 | 25 | 403 | |
75 | 25 | 397 | |
89 | 26 | 376 | |
103 | 26 | 384 | |
123 | 31 | 386 | |
135 | 36 | 403 | 80% seizure reduction |
Case 2 | |||
1 | 5 | 390 | |
8 | 10 | 405 | |
15 | 15 | 380 | |
29 | 20 | 378 | 30% seizure reduction |
QTc=Corrected QT interval