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. 2019 Jul 3;14:4781–4800. doi: 10.2147/IJN.S207666

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© 2019 Wu et al.

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(A) Schematic illustration of the synthetic procedure for the PEG-MnO₂ NSs. (B) Theranostic functionality of the PEG-MnO₂ NSs for intracellular pH-responsive drug release and the axial and coronal T₁-MRI images of 4T1 tumor-bearing nude mice before (a₁, b₁) and after (a₂ – a₉ and b₂ – b₉) administration of the PEG–MnO₂ nanosheets within the tumor and normal subcutaneous tissue. PEG denotes ethylene glycol. Reproduced with permission from Chen Y, Ye D, Wu M, et al. Break-up of two-dimensional MnO2 nanosheets promotes ultrasensitive pH-triggered theranostics of cancer. Adv Mater Weinheim. 2014;26(41):7019–7026.¹⁵⁶ Copyright © 2014, John Wiley and Sons.