S2.

Partial list of differentially overexpressed exosomal microRNAs between HCT116-TP53(R273H) and HCT116-TP53(WT) cells

miRBase accession No.	Systematic name	Fold change	P
MIMAT0004561	hsa-miR-187-5p	4.55	0.0033
MIMAT0004494	hsa-miR-21-3p	2.56	0.0049
MIMAT0023710	hsa-miR-6085	3.25	0.0037
MIMAT0003308	hsa-miR-638	6.85	0.0043
MIMAT0027500	hsa-miR-6800-5p	5.17	0.0028
MIMAT0027583	hsa-miR-6840-3p	2.92	0.0032
MIMAT0027600	hsa-miR-6850-5p	3.99	0.0030
MIMAT0003887	hsa-miR-769-3p	4.55	0.0047
MIMAT0004561	hsa-miR-187-5p	4.55	0.0033
MIMAT0027600	hsa-miR-6850-5p	3.99	0.0030