Table 2.

Primary and secondary outcomes of University of Southern California eye physics plaques compared to results reported by other centers

Outcomes	Other studies	USC
Primary outcomes
Tumor recurrence rate	0–11.6% (11, 13–17)	1.71% (KM estimate of cumulative incidence of local tumor recurrence at 5 years)
Enucleation rate	6–12.5% (11, 17, 18)	3.59% (KM estimate of cumulative incidence of enucleation at 5 years)
Metastases rate	10–13% (11, 13, 16, 17)	11.83% (KM estimate of cumulative incidence of metastases at 5 years)
Secondary outcomes
Preoperative visual acuity
≥20/40–20/50	64.0–70.0% (12, 19)	67.19%
≤20/200	7.1–9.7% (12, 19)	18.75%
Postoperative visual acuity
≥20/40–20/50	34–37.5% (12, 20)	33.08%
≤20/200	22–95% (12, 19, 21)	44.36%
Change in visual acuity
Loss of <2 lines of visual acuity from baseline	26–62% (21)	44.09%
Loss of ≥6 lines of visual acuity from baseline	49% (12)	39.37%
Radiation toxicity rates
Radiation retinopathy	10–63% (7, 18, 21)	42.9%
Optic neuropathy	0–46% (7,18,21)	20.3%

KM = Kaplan–Meier; USC = University of Southern California.