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. 2019 Jul 4;11:6139–6150. doi: 10.2147/CMAR.S200126

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© 2019 Zheng et al.

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Kaplan–Meier curves for 424 cases of lung adenocarcinoma patients with different clinicopathological features.

Notes: (A) Patients with exon 18 mutation had shorter OS than those with exon 19 and exon 21. (B–D) 424 cases of lung adenocarcinoma patients with wild-type EGFR gene, stage IV and poor differentiation had shorter survival. (E and F) 234 cases of mutant EGFR gene with EGFR-TKI treatment and surgery treatment had longer survival. (G and H) 190 cases of wild-type EGFR gene with surgery treatment had longer survival, but EGFR-TKI treatment was not significant (Kaplan–Meier analysis was used to plot the overall survival and statistical significance was assessed by log-rank test).

Abbreviations: OS, overall survival; EGFR, epidermal growth factor receptor; EGFR-TKI, EGFR-tyrosine kinase inhibitor.