Table 3.

Risk of demyelinating diseases of the central nervous system, rather than multiple sclerosis, in patients with and without septicaemia, stratified by age, sex and comorbidity

Variable	Septicaemia cohort			Comparison cohort			Adjusted HR (95% CI)
	Event	PYs	Rate	Event	PYs	Rate
Age group
<45	47	753 379	6.24	21	3 489 202	0.60	6.41 (3.65 to 11.3)**
45–64	51	531 048	9.6	29	3 283 699	0.88	6.66 (3.98 to 11.2)**
≧65	46	798 474	5.76	86	5 579 879	1.54	2.45 (1.65 to 3.62)**
Sex
Female	87	1 060 254	8.21	68	5 924 056	1.15	4.43 (3.12 to 6.29)**
Male	57	1 022 646	5.57	68	6 428 724	1.06	3.89 (2.63 to 5.75)**
Comorbidities
No	115	1 893 501	6.07	130	12 135 849	1.07	3.95 (3.01 to 5.2)**
Yes	29	189 399	15.31	6	216 931	2.77	3.74 (1.50 to 9.27)*

Models adjusted for age, sex and comorbidities listed in table 1.

**p<0.01; **p<0.001.

PYs, person-years;Rate, incidence rate, per 100 000 person-years.