Nuclear pore complex (NPC) structural components. Illustration of the different regions that comprise the NPC: cytoplasmic, nucleoplasmic, and inner rings. Multiple copies of nucleoporins assemble within these regions in a stack-like manner forming subcomplexes. The nucleoporins are separated into corresponding color-coded boxes that signify each subcomplex and their localization within the NPC. Elys, embryonic large molecule derived from yolk sac; gp210, nuclear pore membrane glycoprotein 210; Nup, nucleoporin; Rae1, ribonucleic acid export 1; RANBP2, Ran binding protein 2; Pom121, nuclear envelope pore membrane protein of 121 kDa; TMEM48, transmembrane protein 48; Tpr, translocated promoter region.