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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Chem Biol Interact. 2019 May 30;308:372–376. doi: 10.1016/j.cbi.2019.05.051

Table 1.

Inhibitory activity of computationally selected solanaceous alkaloids (compounds 1 to 3) against human BChE

Compound ID NCI ID Conventional Name Inhibition (%) of BChE at 5 μM Inhibition (%) of AChE at 5 μM IC50 against BChE (nM)
1 76025 Solanidine 100 10 16.8
2 27592 Tomatidine 95 19 346
3 35543 Solasodine 98 2 391
4 734950 44
5 76026 39
6 152144 24
7 23898 22
8 7520 18
9 117607 14
10 117612 8.3