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. Author manuscript; available in PMC: 2019 Jul 8.
Published in final edited form as: J Immunol. 2013 May 31;191(1):407–414. doi: 10.4049/jimmunol.1103779

Figure 5. Muscles of LysMCre/HIF-1α+f/+f mice were characterized by lower XSAs of regenerating myofibers and larger areas of necrotic cell debris during the regeneration phase.

Figure 5

(A) Representative histopathology (H&E staining) at 7 and 10 d after injury. Five to six regenerating myofibers are surrounded in black to give an example how the XSA was measured. (B) The XSA of regenerating myofibers was significantly decreased in LysMCre/HIF-1α+f/+f mice. (C) LysMCre/HIF-1α+f/+f muscles showed significantly larger areas of necrotic cell debris compared with HIF-1α+f/+f mice. Each group included five mice. Scale bars, 100 μm. Data are mean ± SEM. *p ≤ 0.05.