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. 2019 Jul 2;10:421. doi: 10.3389/fendo.2019.00421

Figure 1.

Figure 1

Risk assessment of leukocyte mtDNA-CN z scores in CC. (A) The difference in leukocyte mtDNA-CN z scores between cases and controls in the discovery set; (B) The difference in leukocyte mtDNA-CN z scores between cases and controls in the validation set; (C) Restricted cubic spline for assessing the shape of the association between leukocyte mtDNA-CN z scores and TC risk in the combined set. In, restricted cubic spline, four knots were set at 5th, 35th, 65th, and 95th percentiles of mtDNA-CN z scores. The red line represented the ORs corresponding to the different z scores of mtDNA-CN. The blue dotted line represented the 95%CIs of the ORs. ORs and P-values adjusted for age, sex, BMI, smoking habit, alcohol drinking habit, and history of DM.