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. 2019 Jul 8;10:3009. doi: 10.1038/s41467-019-10598-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Dosage compensation coefficient (DCC) for eQTLs across tissues. DCC is estimated for tissues with at least three eQTLs that satisfied the within tissue Bonferroni significance threshold in each of the 22 tissue-types. A mean of 28 (SD = 18) eQTL are identified in the male discovery analysis giving a mean DCC of 1.94 (SD = 0.16) across 22 tissues. A mean of 5 (SD = 0.82) eQTLs are identified in the female discovery analysis giving mean DCC of 1.59 (SD = 0.13) across seven tissues. The coloured bars represent the standard errors. Males were down-sampled 100 times so that the proportions match that of females within each of the seven tissues, and mean DCC is calculated across the 100 replicates. The grey bars represent the standard deviation across 100 replicates. SD, standard deviation