Figure 1.

Study design. (a) Telemetric ECG devices were implanted in the same procedure as cryo-injury (MI) was performed on day 0. At day 7, all surviving animals received either hEHT or control constructs. The perioperative periods were defined as the first 48 h following each intervention and were excluded from ECG analysis (black time frames). ECG analysis was performed following cryo-injury (day 3–day 6) and following graft implantation (day 10–day 35). Echocardiography (Echo) was performed at days 0, 7 and 35. On day 35, organs were harvested for histological examination. (b) Study flow chart, including animal numbers and details on animal deaths (†).