Table 2.
Stratification analysis of the associations between rs1800796 genotypes and gastric cancer risk
| Variables | Rs1800796 (cases/controls) | AOR (95% CI) | p-valuea | |
|---|---|---|---|---|
|
| ||||
| CC | CG/GG | |||
| Age | ||||
| ≤64 | 115/125 | 96/87 | 1.16 (0.80, 1.70) | 0.432 |
| >64 | 111/143 | 107/100 | 1.67 (1.17, 2.39) | 0.005 |
| Gender | ||||
| Male | 163/187 | 190/171 | 1.30 (0.96, 1.75) | 0.091 |
| Female | 63/81 | 63/44 | 1.82 (1.09, 3.05) | 0.023 |
| H. pylori infection | ||||
| Positive | 121/133 | 140/98 | 1.54 (1.07, 2.22) | 0.019 |
| Negative | 105/135 | 113/117 | 1.28 (0.88, 1.85) | 0.193 |
| Differentiation | ||||
| Low | 93/268 | 99/215 | 1.34 (0.95, 1.89) | 0.091 |
| Median to high | 133/268 | 154/215 | 1.45 (1.08, 1.96) | 0.015 |
| Clinical stage | ||||
| I-II | 76/268 | 83/215 | 1.39 (0.95, 2.01) | 0.088 |
| III-IV | 150/268 | 170/215 | 1.41 (1.06, 1.88) | 0.020 |
| Tumor site | ||||
| Cardia | 72/268 | 66/215 | 1.15 (0.78, 1.68) | 0.493 |
| Non-cardia | 154/268 | 187/215 | 1.53 (1.15, 2.04) | 0.003 |
a
Adjusted for age, gender, smoking, drinking, and H. pylori infection status.
AOR, adjusted odds ratio.