Table 3.

Analysis of associations between genetic variations and clinical outcomes

Genotype	Cases, n	Death, n (%)	Log-rank p-value	HR
IL-4 rs2248
TT	406	255 (0.63)		Reference
GT/GG	54	31 (0.57)	0.734	1.07 (0.74, 1.55)
IL-4 rs2070874
TT	301	192 (0.64)		Reference
TC/CC	159	94 (0.59)	0.417	1.11 (0.87, 1.42)
IL-4R rs2057768
TT	119	72 (0.61)		Reference
CT/CC	341	214 (0.63)	0.451	1.05 (0.92, 1.20)
IL-4R rs2107356
CC	182	108 (0.59)		Reference
TC/TT	278	178 (0.64)	0.317	1.13 (0.89, 1.44)
IL-4R rs1805015
TT	388	241 (0.62)		Reference
CT/CC	72	45 (0.63)	0.745	1.03 (0.88, 1.20)
IL-4R rs1801275
AA	316	197 (0.62)		Reference
GA/GG	144	89 (0.62)	0.843	1.03 (0.80, 1.32)
IL-6 rs6949149
TT	144	88 (0.61)		Reference
GT/GG	316	198 (0.63)	0.510	1.04 (0.92, 1.18)
IL-6 rs10499563
TT	286	183 (0.64)		Reference
TC/CC	174	103 (0.59)	0.417	1.11 (0.87, 1.41)
IL-6 rs1800796
CC	220	137 (0.62)		Reference
GC/GG	240	149 (0.62)	0.952	1.00 (0.89, 1.13)
IL-6R rs2228145
AA	156	96 (0.62)		Reference
CA/CC	304	190 (0.63)	0.873	1.02 (0.80, 1.30)

HR was estimated using the univariate Cox regression model.