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. 2019 Jun 15;11(6):3816–3824.

Figure 1.

Figure 1

Anti-proliferation effects of combination treatments in HCC cells. After treatment with magnolin (25 μM, 50 μM, 75 μM, 100 μM, 125 μM) and SB590885 (3 μM, 6 μM, 9 μM, 12 μM, 15 μM) in combination or single treatment for 48 h, the CCK-8 assay was used to determine cell viability (A) Bel-7402 cell line, (B) SK-Hep1 cell line. These results are mean ± SD of three independent experiments performed in triplicate. **P<0.001 versus single treatments (one-way ANOVA followed by a Student-Newman-Keuls test). The combination of 100 μM magnolin and 12 μM SB590885 significantly inhibited colony formation in cells (C) Bel-7402 cell line (D) SK-Hep1 cell line. These results are mean ± SD of three independent experiments performed in triplicate. **P<0.001 versus single treatments (one-way ANOVA followed by a Student-Newman-Keuls test).