Figure 2.
Inhibition of lncRNA MEG3 decelerates the proliferation and apoptosis of VSMCs. A. Real-time PCR showed the expression of MEG3 in VSMCs in normal condition. B. Real-time PCR showed the expression of MEG3 in VSMCs under ox-LDL treatment. C. Cell proliferation was detected by CCK-8 assay in different groups. D. PCNA, α-SMA and SM22-α mRNA were measured by RT-PCR. E. Western blot assay was used for measurement of proliferation biomarkers including PCNA, α-SMA and SM22-α. F. Flow cytometry was used to assay the apoptosis of VSMCs. Data were represented as mean ± SEM. *P<0.05, **P<0.01, and ***P<0.001.