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HAb18IgG decreased the ratio and potential of CSCs. (A, B) Sphere numbers (A) and sphere size (B) in 2.5, 5, 10, or 20 µg/ml HAb18IgG- or 20 µg/ml nIgG-treated cells. (C, D) ALDH+ subpopulation ratios in MIA PaCa-2 and PANC-1 cells treated with 1 µg/ml or 10 µg/ml HAb18IgG or 10 µg/ml nIgG for 2 days.
