Table 3.

Haplotypes of SNPs with the significance < 0.001 in Saudi female with low VO_2max

CHR	Block	Haplotype	Case, Control Frequencies	Chi Square	P Value	Haplotypes	Risk/Protective
1	Block 1	GAT	0.468, 0.052	13.512	2.00E-04	rs10800201G; rs4657537A; rs4657583T**	Risk
1		GAC	0.236, 0.226	0.009	0.9244	rs10800201G; rs4657537A; rs4657583C
1		AGT	0.156, 0.271	1.302	0.2538	rs10800201A; rs4657537G; rs4657583T
1		AGC	0.048, 0.284	7.097	0.0077	rs10800201A; rs4657537G; rs4657583C	Protective
1		GGT	0.056, 0.034	0.173	0.6777	rs10800201G; rs4657537G; rs4657583T
1		GGC	0.004, 0.091	3.148	0.076	rs10800201G; rs4657537G; rs4657583C
1		AAC	0.002, 0.043	1.425	0.2326	rs10800201A; rs4657537A; rs4657583C
1		AAT	0.031, 0.001	0.831	0.3619	rs10800201A; rs4657537A; rs4657583T
1	Block 2	CG	0.866, 0.497	10.664	0.0011	rs859667C; rs10218696G	Risk
1		TA	0.024, 0.247	7.654	0.0057	rs859667T; rs10218696A	Protective
1		TG	0.055, 0.146	1.577	0.2092	rs859667T; rs10218696G
1		CA	0.055, 0.110	0.683	0.4085	rs859667C; rs10218696A
3	Block 1	GATG	0.605, 0.179	12.016	5.00E-04	rs978979G; rs7637449A; rs111934125T; rs9835332G**	Risk
3		AGCC	0.105, 0.449	10.144	0.0014	rs978979A; rs7637449G; rs111934125C; rs9835332C	Protective
3		AGTC	0.158, 0.229	0.538	0.4634	rs978979A; rs7637449G; rs111934125T; rs9835332C
3		GGTC	0.079, 0.056	0.126	0.7222	rs978979G; rs7637449G; rs111934125T; rs9835332C
3		GGCC	0.053, 0.086	0.294	0.5874	rs978979G; rs7637449G; rs111934125C; rs9835332C
6	Block 1	AC	0.447, 0.821	9.448	0.0021	rs1936797A; rs9491696C	Protective
6		GG	0.447, 0.107	8.836	0.003	rs1936797G; rs9491696G	Risk
6		AG	0.105, 0.071	0.223	0.6365	rs1936797A; rs9491696G
7	Block 1	TGTC	0.814, 0.428	10.542	0.0012	rs11761888T; rs17854248G; rs17164867T; rs968404C	Risk
7		CTCT	0.131, 0.428	7.432	0.0064	rs11761888C; rs17854248T; rs17164867C; rs968404T	Protective
7		CGTC	0.054, 0.036	0.127	0.7217	rs11761888C; rs17854248G; rs17164867T; rs968404C
7		CTCC	0.000, 0.036	1.371	0.2416	rs11761888C; rs17854248T; rs17164867C; rs968404C
7		TGTT	0.000, 0.036	1.371	0.2416	rs11761888T; rs17854248G; rs17164867T; rs968404T
7		CTTC	0.000, 0.036	1.378	0.2404	rs11761888C; rs17854248T; rs17164867T; rs968404C
8	Block 1	GT	0.947, 0.679	8.386	0.0038	rs13277113G; rs2618476T	Risk
8		AC	0.053, 0.321	8.386	0.0038	rs13277113A; rs2618476C	Protective
11	Block 1	CGCA	0.868, 0.500	10.674	0.0011	rs1030726C; rs1030723G; rs11033800C; rs11033801A	Risk
11		AGAG	0.105, 0.214	1.49	0.2221	rs1030726A; rs1030723G; rs11033800A; rs11033801G
11		AAAG	0.026, 0.286	9.211	0.0024	rs1030726A; rs1030723A; rs11033800A; rs11033801G	Protective
14	Block 1	TCGTT	0.737, 0.357	9.515	0.002	rs12891553T; rs34693535C; rs17211285G; rs17277221T; rs17277228T	Risk
14		CTTCC	0.263, 0.643	9.515	0.002	rs12891553C; rs34693535T; rs17211285T; rs17277221C; rs17277228C	Protective
16	Block 1	TG	0.842, 0.500	8.933	0.0028	rs1134760T; rs5923G	Risk
16		CA	0.079, 0.357	7.888	0.005	rs1134760C; rs5923A	Protective
16		CG	0.079, 0.143	0.694	0.4046	rs1134760C; rs5923G
17	Block 1	CC	0.763, 0.295	14.384	1.00E-04	rs13696C; rs1901187C**	Risk
17		CT	0.184, 0.241	0.314	0.575	rs13696C; rs1901187T
17		TT	0.000, 0.331	14.608	1.00E-04	rs13696T; rs1901187T*	Protective
17		TC	0.053, 0.134	1.335	0.2479	rs13696T; rs1901187C
19	Block 1	TA	0.342, 0.750	10.739	0.001	rs4801433T; rs4801200A	Protective
19		CT	0.658, 0.250	10.739	0.001	rs4801433C; rs4801200T	Risk

CHR: Chromosome number;

^**Risk haplotypes (P < 1.0 × 10^-4);

^*Protective haplotypes (P < 1.0 × 10^-4).