Figure 1.

Reverse transcription-quantitative PCR analysis of differentially expressed mRNAs in three genes, mTOR, RPTOR and RICTOR, in 5 human colorectal cancer cell lines. The expression levels of all genes were elevated in all cell lines (stimulated with 200 nM insulin) compared with normal FHC cells. In the RICTOR bar graph, error bars are included but are small. **P<0.01; ***P≤0.001. Number of repeats, 3. mTOR, mammalian target of rapamycin; RPTOR, regulatory-associated protein of mTOR complex I; RICTOR, rapamycin-insensitive companion of mTOR.