Table V.

miRNA candidates targeting the RICTOR gene predicted by bioinformatics analysis.

					Database algorithm
miRNA ID	Proposed target gene	Ensembl gene ID	miRNA sequence		Diana	miRWalk	TargetScan	PicTar	miRDB
hsa-miR-495	RICTOR	ENSG00000164327	AAACAAACAUGGUGCACUUCUU	Score	0.871	–	−0.17	–	–
				P-value	0.002	0.0166	N/A	–	–
				Binding	8mer	9mer	8mer	–	–
				Region	UTR3	UTR3	UTR3	–	–
hsa-miR-194-5p	RICTOR	ENSG00000164327	UGUAACAGCAACUCCAUGUGGA	Score	0.79	–	–	–	83
				P-value	0.003	–	–	–	Rank 28
				Binding	6mer	–	–	–	7mer
				Region	UTR3	–	–	–	UTR3
hsa-miR-659-3p	RICTOR	ENSG00000164327	CUUGUUCAGGGAGGGUCCCCA	Score	0.986	–	–	–	75
				P-value	0.008	–	–	–	Rank 48
				Binding	7mer	–	–	–	7mer
				Region	UTR3	–	–	–	UTR3
hsa-miR-142-3p	RICTOR	ENSG00000164327	UGUAGUGUUUCCUACUUUAUGGA	Score	0.999	–	–	–	100
				P-value	0.03	0.0166	0.99	–	Rank 61
				Binding	8mer	9mer	8mer	–	7mer
				Region	UTR3	UTR3	UTR3	–	UTR3
hsa-miR-98-5P	RICTOR	ENSG00000164327	UGAGGUAGUAAGUUGUAUU	Score	0.999	–	−0.14	–
				P-value	0.007	0.0166	0.98	–	Rank
				Binding	8mer	9mer	8mer	–	7mer
				Region	UTR3	UTR3	UTR3	–	UTR3
hsa-miR-1323	RICTOR	ENSG00000164327	UCAAAACUGAGGGGCAUUUUCU	Score	0.75	–	–	–	80
				P-value	0.006	0.004	–	–	Rank 37
				Binding	8mer	10mer	–	–	7mer
				Region	UTR3	UTR3	–	–	UTR3

miRNA, microRNA; miR, microRNA; UTR3, 3 untranslated region; RICTOR; rapamycin-insensitive companion of mammalian target of rapamycin.