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. 2019 Jun 4;84(13):8531–8541. doi: 10.1021/acs.joc.9b00884

Table 4. Pharmacological and Ecological Activities of 1–2.

assay 1 2
P. berghei EC50 (μM)a 2.4 5.8
MRSA MIC90 (μg/mL) 16.7 ± 0.3 >50
HaCaT toxicity (μM)b >50 >50
D. salina IC50 (μM) 0.14 NT
a

Exoerythrocytic (liver) stage of P. berghei.

b

Human skin keratinocytes, NT—not tested.