TABLE 3.

Ontogeny-based predicted UGT/SULT f_m values of acetaminophen across different age groups.

Mean, lower, and higher 95% CI of the proteomics data for DMEs were considered for prediction of f_m of DMEs.

Age Groups (Mean, Range)	UGT/SULT fm
	Mean	Lower 95% CI	Higher 95% CI
Neonatal (14 day, 0–27 day)	0.46	0.12	0.55
Infancy (6 mo, 28–364 day)	0.54	0.62	0.50
Infancy (1 yr, 29 to <2 yr)	0.44	0.49	0.42
Toddler/early childhood (4 yr, 1 to <6 yr)	0.47	0.45	0.48
Middle childhood (9 yr, 6 to <12 yr)	0.64	0.62	0.64
Children (7 yr, 2 to <12 yr)	0.56	0.56	0.56
Adolescence (14 yr, 12–16 yr)	1.02	1.18	0.91
Adolescence (15 yr, 12–18 yr)	0.97	1.08	0.90
Adulthood (30 yr, > 18 yr)	1.71	1.60	1.86

95% CI, 95% confidence interval.