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. 2019 May 27;47(12):6114–6129. doi: 10.1093/nar/gkz471

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Completion of high-quality genome sequence of Streptomyces clavuligerus ATCC 27604. (A) Correction of genome annotation of S. clavuligerus. The 433 ‘removed’ genes were not added to the total number of genes. (B) Examples of corrected genes with functional annotations. (C) BGC distribution of three Streptomyces species. Scla_chr, the chromosome of S. clavuligerus; Scla_pla, the mega-plasmid of S. clavuligerus; Scla, total genome of S. clavuligerus; Sco, the genome of Streptomyces coelicolor; Save, the genome of Streptomyces avermitilis.