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. 2019 Jul 4;12:1013–1021. doi: 10.2147/DMSO.S206867

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© 2019 Yang et al.

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Body weight, fasting blood glucose levels, HOMA-IR scores, ALT and AST in mice after Liraglutide (L) or saline (S) treatment. Data were mean±SD (n=6 each group). (A) BW; (B) FBG level; (C) HOMA-IR score; (D) ALT; (E) p-values for the interactive effects of HFD and Liraglutide treatment on BWs, FBG levels, HOMA-IR scores, ALT and AST were 0.055, 0.001, 0.005, 0.185 and 0.001, respectively. *p<0.05 for comparison between saline and Liraglutide treatments. ^#p<0.05 for comparison between NC and HFD groups.

Abbreviations: HOMA-IR, homeostasis model assessment of insulin resistance; ALT, alanine aminotransferase; AST, aspartame aminotransferase; BW, body weight; FBG, fasting blood glucose; HFD, high-fat diet; NC, the mice fed with a normal chow diet.