Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 4;12:1013–1021. doi: 10.2147/DMSO.S206867

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Yang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

InsR, IGF-1R, IRS2, PI3K p85, Akt and α -SMA mRNA expression levels in mice after Liraglutide (L) or saline (S) treatment. Data were mean±SD (n=6 each group). p-values for the interactive effects of HFD and Liraglutide treatment on InsR, IGF-1R, IRS2, PI3K p85, Akt and α -SMA mRNA expression levels were 0.05, 0.338, 0.253, 0.53, 0.001 and 0.087, respectively. ie, InsR (A); IGF-1R (B); IRS2 (C); PI3K p85 (D); Akt (E); α -SMA (F). *p<0.05 for the comparison of the saline and Liraglutide groups; ^#p<0.05 for the comparison of NC and HFD groups.

Abbreviations: InsR, insulin receptor; IGF-1R, insulin-like growth factor-1 receptor; IRS2, insulin receptor substrate 2; PI3K p85, PI3 kinase p85; Akt, protein kinase B; α -SMA, α - smooth muscle actin; HFD, high-fat diet; NC, the mice fed with a normal chow diet.