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. 2019 Jul 3;14:4817–4831. doi: 10.2147/IJN.S206294

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© 2019 Zhao et al.

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In vivo anti-arterial thrombosis and thrombolytic activity, as well as downregulation of the expression of GPIIb/IIIa and P-selectin. (A) Dose-dependently anti-arterial thrombosis activities of MTCA-KKV; (B) Thrombolytic activity of 0.01 μmol/kg MTCA-KKV; (C) GPIIb/IIIa expression of the rats treated with 0.01 μmol/kg MTCA-KKV; (D) P-selectin expression of the rats treated with 0.01 μmol/kg MTCA-KKV; n=12.

Abbreviations: NS, normal saline; MTCA, (1R,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid; MTCA-KKV, (1R,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxyl-Lys(Pro-Ala-Lys)-Arg-Gly-Asp-Val.