Table 1.
Baseline Patient Characteristics Before Propensity Score Adjustments, by Treatment Group.
Variable | Bisphosphonates (N=39493) |
Teriparatide (N=550) |
P-value |
---|---|---|---|
Age (%) | 0.089 | ||
<65 | 8.78 | 11.45 | |
65–74 | 47.54 | 46.00 | |
≥75 | 43.68 | 42.55 | |
Race (%) | <0.001 | ||
White | 77.30 | 78.00 | |
Black | 6.17 | 2.91 | |
Asian | 5.60 | 2.73 | |
Hispanic | 9.44 | 14.73 | |
Native American | 0.48 | 0.91 | |
Other | 1.03 | 0.70 | |
Medicaid eligibility (%) | 36.16 | 45.82 | <0.001 |
History of hip fracture (%) | 4.66 | 11.80 | <0.001 |
History of vertebral fracture (%) | 5.50 | 19.10 | <0.001 |
History of fracture of radius, ulna or carpal bones (%) | 3.20 | 5.27 | 0.006 |
History of other upper limb fractures (%) | 3.24 | 5.27 | 0.008 |
History of other lower limb fractures (%) | 6.46 | 13.27 | <0.001 |
History of CMS priority cancera (%) | 10.61 | 7.09 | 0.008 |
No. of CMS priority comorbiditiesb (%) | <0.001 | ||
0–2 | 46.11 | 35.45 | |
3–5 | 36.96 | 39.27 | |
≥6 | 16.93 | 25.27 | |
Time between diagnosis and drug initiation | <0.001 | ||
≤2 months | 51.44 | 34.36 |
NOTES:
Abbreviations: CMS= Centers for Medicare and Medicaid Services.
CMS priority types of cancer include breast cancer, colorectal cancer, endometrial cancer and lung cancer.
The number of other CMS priority comorbidities was calculated as the sum of previous history of acute myocardial infarction, atrial fibrillation, Alzheimer’s disease, related disorders or senile dementia, cataract, chronic kidney disease, chronic obstructive pulmonary disease, congestive heart failure, depression, diabetes, glaucoma, ischemic heart disease, history of stroke or transient ischemic attack, and rheumatoid arthritis or osteoarthritis.