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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: Cancer Causes Control. 2019 Mar 23;30(5):537–547. doi: 10.1007/s10552-019-01157-3

Table 2.

Association between smoking, BMI, physical inactivity, and composite lifestyle variables and overall survival among ovarian cancer cases, Ovarian Cancer Association Consortium1.

Variables Status
HR(95%CI)2 p-value
Died Alive
Smoking
   Never 2075 1746 1.00(ref)
   Former 584 371 1.10 (1.03–1.18) <0.001
   Current 1337 909 1.22 (1.11–1.34) 0.005

BMI at the time period preceding diagnosis
   Underweight 77 63 1.04 (0.82–1.30) 0.75
   Normal weight 1899 1415 1.00(ref)
   Overweight 1139 872 1.02 (0.95–1.10) 0.58
   Obese 881 676 1.16 (1.07–1.25) <0.001

Recreational physical inactivity
   Active 2895 2253 1.00(ref)
   Inactive 1100 771 1.08 (1.01–1.16) 0.03

Combined exposure to smoking, overweight/obesity, and physical inactivity
Smoking Overweight/Obese Inactive
Never No No 762 641 1.00(ref)
Former No No 487 365 1.03 (0.92–1.15) 0.62
Current No No 187 118 1.19 (1.01–1.40) 0.03
Never Yes No 758 631 1.06 (0.95–1.17) 0.28
Never No Yes 198 156 1.03 (0.88–1.31) 0.73
Never Yes Yes 321 275 1.05 (0.92–1.19) 0.50
Former Yes No 491 344 1.16 (1.03–1.30) 0.01
Former No Yes 143 72 1.21 (1.01–1.45) 0.04
Former Yes Yes 198 122 1.35 (1.15–1.59) <0.001
Current Yes No 159 110 1.28 (1.08–1.52) 0.005
Current No Yes 121 62 1.26 (1.04–1.54) 0.02
Current Yes Yes 94 65 1.37 (1.10–1.70) 0.004
1

Results for the individual models for each factor

2

Cox proportional hazards model adjusted for age at diagnosis (continuous), stage, and study site