Figure 1:

Flow diagram overview of in vivo investigations of 40 matrix-associated stem cell implants (MASIs) in 20 knee joints of 10 Göttingen minipigs. Pilot studies for scaffold and labeling optimization were performed in two minipigs. Two MASIs dislocated. For the main arm of the study, 20 ferumoxytol-labeled MASIs and 12 unlabeled MASIs were assessed.