Table 2.

Sample collection methods and time of sample collection in relation to onset of chest pain/hospital admission of the included studies.

	Apple et al. [31]	Baldus et al.∗ [34]	Brugger-Andersen et al. [30]	Cavusoglu et al. [38]	Chang et al. [28]	Eggers et al. [9]	Kaya et al. [10]	Koch et al. [26]	Mocatta et al. [27]	Morrow et al. [39]	Rahman et al. [32]	Scirica et al. [29]
Sample collection method	Heparin-containing tubes	NR	Citrate-anticoagulated tubes	NR	NR	EDTA-anticoagulated tubes	NR	EDTA-anticoagulated tubes	EDTA-anticoagulated tubes	Citrate-anticoagulated tubes	NR	EDTA-anticoagulated tubes
Time of sample collection	Within 3.1 hours from the onset of symptoms	Within 8.7 hours from the onset of symptoms	Within 4-6 days from the onset of symptoms	≥12 hours after hospital admission	At hospital admission	After 0.8 hour from hospital admission	Within 6 hours of the onset of symptoms	After 26.1 hours from hospital admission	From 24 to 96 hours after hospital admission	NR	NR	NR

^∗Oemrawsingh et al. is a longer follow-up report of Baldus et al.'s study; the study's subjects received heparin before blood samples were withdrawn.