Table 1.
Main procedure-related clinical adverse events by CTCAE grades in both groups.
| CTCAE | Group | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | All grades | P value |
|---|---|---|---|---|---|---|---|---|
| Abdominal pain | TACE-GKR (n=94) | 10(10.64) | 1(1.06) | 0 | 0 | 0 | 11(11.7) | 0.430 |
| Jiedu plus TACE-GKR (n=96) | 8(8.33) | 0 | 0 | 0 | 0 | 8(8.33) | ||
| Anorexia | TACE-GKR (n=94) | 12(12.77) | 14(14.89) | 4(4.26) | 0 | 0 | 30(31.91) | 0.301 |
| Jiedu plus TACE-GKR (n=96) | 8(8.33) | 15(15.63) | 1(1.04) | 0 | 0 | 24(25) | ||
| Ascites | TACE-GKR (n=94) | 3(3.19) | 1(1.06) | 0 | 0 | 0 | 4(4.26) | 0.991 |
| Jiedu plus TACE-GKR (n=96) | 2(2.08) | 2(2.08) | 0 | 0 | 0 | 4(4.17) | ||
| Constipation | TACE-GKR (n=94) | 3(3.19) | 1(1.06) | 0 | 0 | 0 | 4(4.26) | 0.967 |
| Jiedu plus TACE-GKR (n=96) | 4(4.17) | 0 | 0 | 0 | 0 | 4(4.17) | ||
| Dermatitis | TACE-GKR (n=94) | 12(12.77) | 4(4.26) | 0 | 0 | 0 | 16(17.02) | 0.728 |
| Jiedu plus TACE-GKR (n=96) | 14(14.58) | 1(1.04) | 0 | 0 | 0 | 15(15.63) | ||
| Fatigue | TACE-GKR (n=94) | 14(14.89) | 15(15.96) | 0 | 0 | 0 | 29(30.85) | 0.362 |
| Jiedu plus TACE-GKR (n=96) | 16(16.67) | 9(9.38) | 0 | 0 | 0 | 25(26.04) | ||
| Fever | TACE-GKR (n=94) | 21(22.34) | 4(4.26) | 0 | 0 | 0 | 25(26.6) | 0.755 |
| Jiedu plus TACE-GKR (n=96) | 17(17.71) | 6(6.25) | 0 | 0 | 0 | 23(23.96) | ||
| Ileus | TACE-GKR (n=94) | 6(6.38) | 0 | 0 | 0 | 0 | 6(6.38) | 0.144 |
| Jiedu plus TACE-GKR (n=96) | 2(2.08) | 0 | 0 | 0 | 0 | 2(2.08) | ||
| Nausea/vomiting | TACE-GKR (n=94) | 24(25.53) | 5(5.32) | 0 | 0 | 0 | 29(30.85) | 0.143 |
| Jiedu plus TACE-GKR (n=96) | 19(19.79) | 1(1.04) | 1(1.04) | 0 | 0 | 21(21.88) | ||
| Pneumonitis | TACE-GKR (n=94) | 1(1.06) | 3(3.19) | 0 | 0 | 0 | 4(4.26) | 0.401 |
| Jiedu plus TACE-GKR (n=96) | 0 | 2(2.08) | 0 | 0 | 0 | 2(2.08) |
CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events. GKR: gamma knife radiosurgery. TACE: transarterial chemoembolization.