Table 2.
The KEGG and GO pathway analysis.
| Term | P value | Benjamini | Related proteins |
|---|---|---|---|
| KEGG Term | |||
| Glutathione metabolism | 0.00079 | 0.025 | P09211, P28161, P09488 |
| Drug metabolism - cytochrome P450 | 0.0014 | 0.022 | P09211, P28161, P09488 |
| Metabolism of xenobiotics by cytochrome P450 | 0.0017 | 0.018 | P09211, P28161, P09488 |
| Chemical carcinogenesis | 0.0019 | 0.015 | P09211, P28161, P09488 |
| Glycerophospholipid metabolism | 0.08 | 0.41 | P22303, P47712 |
| Go Term (Biological Process) | |||
| glutathione derivative biosynthetic process | 0.000034 | 0.0039 | P09211, P28161, P09488 |
| glutathione metabolic process | 0.00023 | 0.013 | P09211, P28161, P09488 |
| cellular detoxification of nitrogen compound | 0.0013 | 0.046 | P28161, P09488 |
| nitrobenzene metabolic process | 0.0017 | 0.046 | P28161, P09488 |
| metabolic process | 0.002 | 0.045 | P09211, P28161, P09488 |
| xenobiotic catabolic process | 0.0029 | 0.053 | P28161, P09488 |
| linoleic acid metabolic process | 0.0071 | 0.11 | P09211, P28161 |
| cellular oxidant detoxification | 0.029 | 0.34 | P09211, P28161 |
| Go Term (Cellular Component) | |||
| cytosol | 0.003 | 0.086 | P11217, P09211, P28161, P30520, P09488, P47712 |
| cytoplasm | 0.024 | 0.3 | P11217, P09211, P28161, P30520, P09488, P47712 |
| extracellular exosome | 0.079 | 0.56 | P11217, P09211, P28161, P30520 |
| Go Term (molecular function) | |||
| glutathione binding | 8.1E-06 | 0.00033 | P09211, P28161, P09488 |
| glutathione transferase activity | 0.000087 | 0.0018 | P09211, P28161, P09488 |
| acetylcholinesterase activity | 0.00083 | 0.011 | P22303, P06276 |
| cholinesterase activity | 0.0012 | 0.013 | P22303, P06276 |
| enzyme binding | 0.0076 | 0.061 | P28161, P09488, P06276 |
| glutathione peroxidase activity | 0.0087 | 0.058 | P09211, P28161 |
| beta-amyloid binding | 0.014 | 0.079 | P22303, P06276 |
| protein homodimerization activity | 0.034 | 0.16 | P28161, P09488, P22303 |
| transferase activity | 0.039 | 0.17 | P09211, P09488 |