Skip to main content
. 2019 Jun 25;2019:1431726. doi: 10.1155/2019/1431726

Figure 2.

Figure 2

The JSD-induced inhibitory effects on the migration and invasion ability of the colon cancer cells in vitro. The experimental group consisted of control, EMT, and JSD. The EMT and JSD groups were treated with 50 ng/mL EGF for 48 h. Next, the JSD group was treated with 6 mg/mL JSD for 48 h. ((a)–(b)) Compared with the control group, the migration distance of the EMT group was significantly increased (P < 0.01), whereas the migration distance of the JSD group was remarkably decreased (P < 0.001). In addition, the migration distance of the JSD group was significantly shorter than that in the EMT group (P < 0.001). ((c)–(f)) The number of transmembrane cells in the EMT group was observed to be upregulated in comparison with that in the control group (both, P < 0.001), whereas the number of transmembrane cells in the JSD group was significantly downregulated in comparison with the control group (both, P < 0.001). At the same time, compared with the EMT group, the number of transmembrane cells in the JSD group was significantly reduced (both, P < 0.001). ∗∗ P < 0.01, ∗∗∗ P < 0.001; n = 9.