TABLE 1.
Baseline Characteristics of 33,368 Patients With and Without PVT at the Time of Transplantation
| PVT (n = 2096) | No PVT (n = 31,272) | P Value | |
|---|---|---|---|
| Recipient characteristics | |||
| Age at listing, years | 53.14 (52.72–53.55) | 52.14 (52.03–52.26) | <0.001 |
| Age at transplant, years | 53.80 (53.38–54.21) | 52.60 (52.49–52.71) | <0.001 |
| Sex, male | 1424 (66.70) | 20,832 (66.62) | 0.21 |
| African American race | 158 (7.54) | 3217 (10.29) | <0.001 |
| Etiology of liver disease | |||
| Alcohol alone | 331 (15.79) | 4881 (15.61) | 0.82 |
| Autoimmune disease | 76 (3.63) | 1045 (3.34) | 0.48 |
| Cholestatic disease | 183 (8.73) | 3237 (10.35) | 0.018 |
| Hepatitis B | 50 (2.39) | 866 (2.77) | 0.30 |
| HCV | 820 (39.12) | 13,282 (42.47) | <0.001 |
| NASH | 252 (12.02) | 2250 (7.19) | <0.001 |
| Other | 384 (18.32) | 5711 (18.26) | 0.95 |
| Severity of liver disease | |||
| MELD score at listing | 19.45 (19.10–19.81) | 19.71 (19.61–19.81) | 0.20 |
| MELD score at transplantation | 23.29 (22.89–23.69) | 22.64 (22.53–22.75) | <0.001 |
| Laboratory values | |||
| Serum bilirubin, mg/dL | 9.15 (8.66–9.65) | 9.38 (9.25–9.51) | 0.39 |
| INR | 1.92 (1.88–1.96) | 1.88 (1.87–1.89) | 0.14 |
| Serum albumin, g/dL | 2.96 (2.93–2.99) | 2.96 (2.95–2.96) | 0.75 |
| Creatinine, g/dL | 1.66 (1.60–1.71) | 1.67 (1.65–1.69) | 0.67 |
| On dialysis at transplantation | 274 (13.09) | 4873 (10.39) | 0.12 |
| Portal hypertension manifestations | |||
| Ascites grade > 2 at transplant | 735 (35.07) | 9886 (31.61) | 0.001 |
| Hepatic encephalopathy > 2 at transplant | 253 (12.07) | 3487 (11.15) | 0.20 |
| NASH risk factors | |||
| Diabetes | 588 (28.05) | 6772 (21.66) | <0.001 |
| BMI at transplant, kg/m2 | 28.16 (27.91–28.42) | 27.89 (27.83–27.95) | 0.04 |
NOTE: Data are given as n (%) or mean (95% CI).