Table 3.
Association Between Baseline Lipid and Apolipoprotein Levels and Atherosclerotic Cardiovascular Disease
| HR (95% CI) | P | |
|---|---|---|
| Total cholesterol, per 1 SD greater | 1.0S (0.92–1.14) | 0.6 |
| Non—HDL-C, per 1 SD lower | 1.09 (0.99–1.21) | 0.07 |
| VLDL-C,a per 1 SD greater | 1.09 (0.99–1.21) | 0.07 |
| Triglycerides,a per 1 SD greater | 1.14 (1.0S-1.25) | 0.01 |
| LDL-C, per 1 SD greater | 1.05 (0.94–1.16) | 0.4 |
| Apolipoprotein B, per 1 SD greater | 1.09 (0.99–1.21) | 0.08 |
| HDL-C, per 1 SD greater | 1.28 (1.09–1.59) | 0.002 |
| Apolipoprotein AI, per 1 SD lower | 1.25 (1.07–1.45) | 0.004 |
Note: Model adjusted for age, sex, race/ethnicity, clinical site, smoking, diabetes mellitus, body mass index, systolic blood pressure, statin use, estimated glomerular filtration rate, and 24-hour urine protein excretion.
Abbreviations: CI, confidence interval; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; LDL-C, low-density lipoprotein cholesterol; non—HDL-C, non lowdensity lipoprotein cholesterol.
Values were natural-log transformed.