Fig. 3.

The endocrine index of transplanted islets. a–h Representative images following insulin (a–d) and glucagon (e–h) immunohistochemical staining of 150 or 225 islets that were transplanted under the kidney capsule, either alone or with AD-MSCs, at 6 weeks following transplantation. Arrows indicate islets present within the representative images. i Quantification of the positive staining endocrine area in samples where 150 or 225 islets were either transplanted alone (white square) or with AD-MSCs (black square). Significant differences: ^aP <0.05 for islets alone vs. islets + AD-MSCs; ^bP <0.05, 150 vs. 250 islets (Student’s unpaired t test)